Guide :

hysterectomy vs. tamoxifen

I was diagnosed with pleomorphic invasive lobular carcinoma  4 node pos.ER and PR pos.stage IIIA July '08. I have since had a bilateral mastectomy with immediate tram reconstruction followed by 4A/C, 4 taxotere and 33 radiation therapy treatments. I am now on tamoxifen and have been experiencing depression, extreme fatigue( weakness) with any physical exertion other than just walking. Is a hysterectomy a better alternative to taking tamoxifen or would I still need to take it?

Research, Knowledge and Information :

Hysterectomy instead of tamoxifen? -

Question from Tracey: Would it not be better to have a hysterectomy than have to take tamoxifen? Answers - Sandra F. Schnall, M.D. Actually some people consider ...
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Breast Cancer Topic: Hysterectomy VS. Tamoxifen?? Any ...

Breast Cancer Discussion Forums - Access the shared knowledge of thousands of people affected by breast cancer
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Can anyone offer insight on tamoxifen vs hysterectomy or ...

Thank you for your insight and knowledge. My first question is : Isn't tamoxifen extremely hard on your body ? 2:) Will I accomplish the same thing with hysterectomy ...
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Hysterectomy vs. Tamoxifen - Susan G. Komen for the Cure

My doctor is suggesting a total hysterectomy rather then take the Tamoxifen. I have suffered with depression/anxiety for years, will this increase after having my ...
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Hysterectomy After Tamoxifen? - Breast cancer - Discussion ...

Breast cancer is the most common cancer in women in the UK. ... May I also ask why do you have to have a hysterectomy after taking Tamoxifen, are you in pain or ...
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Why get an oophorectomy? -

Why get an oophorectomy? ... Question from Kimmy Too: If tamoxifen is a "medical" oophorectomy, ... Hysterectomy instead of tamoxifen?
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Total Hysterectomy while taking Tamoxifen - Treato

Total Hysterectomy while taking Tamoxifen? 517 conversations on the web about experiences with taking Tamoxifen before or after having a Total Hysterectomy
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Tomoxifen vs Hysterectomy | Cancer Survivors Network

about 18 mths ago I had total hysterectomy (as stated in past posts) due to the tamoxifen (enlarging my uterus big time) Any how I didnt' realize I still need to see ...
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Hysterectomy with Estrogen+ Breast Cancer - Navigating Care

Hysterectomy with Estrogen+ Breast Cancer ... I was told that after the hysterectomy I would be taken off Tamoxifen and put on a different medication.
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Tamoxifen and hysterectomy - Camusat

Our tamoxifen and hysterectomy required new slides on account ... The date of the difference between nolvadex tamoxifen in target order between e.g and and/or was ...
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Suggested Questions And Answer :


Hi. How are you? Tamoxifen can increase the risk of development of uterine cancer.  That is the reason why women taking tamoxifen are advised to regularly follow-up with the doctor and undergo pelvic examination.  Patients with abnormal vaginal bleeding and pelvic pain, as well as thickening of the endometrial lining should be evaluated further.  Hysterectomy may be an option for symptomatic patients especially if there is excessive vaginal bleeding.  You may want to discuss treatment options to your doctor. Good luck.
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hysterectomy vs. lupron plus femara

Hi, Your doctors, who know all the specifics of you med. hx and current situation are a far better source  of advice in this matter than anyone over the Internet. However, here is some information from a recent study to add to the mix along with many other consideraions: "Some women decide to have oopherectomy if there is a  family hx of ovarian cancer or they  are at high risk as determined by genetic testing. When  this is not the case, however, a  recent study that  has raised question about the benefit of that step. Statistical analysis showed that during the 25 years of follow-up, women who  had removal of normal ovaries had a higher all-cause mortality rate, mainly from coronary heart disease and lung cancer. Although there was a lower incidence of breast cancer, ovarian cancer, and in fact all cancers in the women who had their ovaries removed, the risk of death from cancer was higher. At no stage of the study was survival higher for the women whose ovaries were removed. The increase in cardiovascular risk and mortality has been found in other studies, although none this large. For women who are not at increased risk of ovarian cancer, prophylactic ovary removal may not be beneficial, and needs to be reconsidered. Source: OBSTETRICS & GYNECOLOGY (113: 1027, '09) " Best wishes...
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hysterectomy vs. tamoxifen

Having a hysterectomy would have nothing to do with your taking Tamoxifen or not. The ovaries are the Estrogen producers so unless they were removed the hormone would still be produced.  Regards .....
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Tamoxifen after hysterectomy

I had a Hysterectomy and I am still taking Tamoxifen.  My first Oncologist said I couldn't take it after a Hysterectomy, but my new one said that it is fine.
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Hi, Gall stones have been linked to Tamoxifen in some subsets of breast cancer patients. The symptoms that you provide do indicate a gall bladder pathology. The treatment for gall stones depends on the symptoms and the patients profile. There are various options available and surgery is not the only option. On the other hand you should consult your doctor and find out whether the detox method you mentioned has been proven to be effective and safe before you try it. Your doctor would be able to guide you with the modality best suited for your profile. Please let us know if you have any queries. Also keep us posted on your health. Good luck.
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DCIS & Tamoxifen

Hi.  Tamoxifen is a necessary treatment for your case (I'm assuming that your tumor is hormone receptor positive). Without tamoxifen, you have approximately 20.3% chance of cancer recurrence in ten years.  Tamoxifen reduces the chances of recurrence to 13% in ten years.  These statistics were calculated using a program called Adjuvant online, which factors in various patient characteristics such as age, tumor size and grade, etc. to come up with estimates of survival and recurrence.
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I suppose if a hysterectomy is recommended then there is a reason ..... I believe I would get a second opinion to help in making the decision. You do realize that in order to block the production of Estrogen you would have to also have your ovaries removed and not just the uterus. One of the side effects of Tamoxifen is vaginal bleeding so I don't find your situation all that rare.     Regards .....
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Breast cancer to hysterectomy

Hi! I, also, had a mastectomy and was on tamoxifen.  However, I was allergic to the tamoxifen and will need a hysterectomy/oop.  It is scheduled for 10/13.  Can't relate to the lymphedema as I haven't experienced any of these symptoms.
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DCIS and Tamoxifen

Ductal Carcinoma In Situ (DCIS) is a noninvasive carcinoma.  The cancer cells are confined to the ductal structures.   DCIS can be treated by: excision (lumpectomy or breast conserving surgery) plus radiotherapy to the breast, excision alone, or mastectomy.  Tamoxifen may or may not be given after surgery.  There is currently no consensus regarding the optimal treatment of DCIS. There was a clinical trial called NSABP B-24 where Tamoxifen was given after lumpectomy and radiotherapy which showed a decrease in ipsilateral local recurrence, contralateral breast cancer, and all breast cancer events. Here is the link of the said clinical trial: However, in another trial called UK DCIS trial, there was no statistically significant difference in the rate of ipsilateral local recurrence, contralateral breast cancer, and all breast cancer events with the addition of tamoxifen after surgery and radiation therapy. You need to discuss with your oncologist your treatment options, weighing the risks and benefits of treatment. Good luck.
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Why should I take Tamoxifen

Even though you have had a hysterectomy, one of the three types of estrogen, Estrone, is still produced by body tissues, especially fat and muscle.  The tamoxifen also blocks this type of estrogen from fueling the growth of cancer cells. I think that you should talk with your doctor about your side effects and see what can be done to mitigate them.  Evaluate your treatment plan and side effects and whether aromatase inhibitors might be a treatment option.  Antidepressants or other measures may provide relief, while not compromising your treatment. Thinking of you (and sharing the night sweats.)
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