Invasive lobular carcinoma
About 75-80% of invasive breast cancers are ductal (IDC) and 10-15% are lobular (ILC).
I'm not aware of the latter type of BC running in families. However, an increasted risk for it is associated with the use of combination estrogen/progestin HRT, so avoiding that medication is probably the main thing you can do to avoid lobular BC. (One study found that women who took that form of HRT for 3 years or more had 4 times the risk for ILC.)
By way of history,there was an observable increase in BC, particularly invasive lobular BC, a number of years ago when HRT was being heavily prescribed, due to being promoted as preventing loss of bone density, heart disease, and cognitive problems, in additional to treating menopausal symptoms.
One study reported that women then currently taking HRT were about three times as likely as other women to be among the cancer patients and those who used combined HRT for three or more years had a higher risk of lobular cancer. They said that incidence of invasive lobular cancer rose by 52 percent in the United States between 1987 and 1999 and that cases of ductal-lobular breast cancer rose by 96 percent during that time, while rates of ductal cancer rose only 3 percent over the same period. They concluded,"Our research suggests that the use of post-menopausal hormone-replacement therapy, specifically the use of combined estrogen-plus-progestin preparations, may be contributing to this increase."
Since then, many women made the decision to stop HRT and doctors began recommending only using the lowest effective dose, for the shortest period of time possible, to treat menopause symptoms that significantly affect a woman's quality of life, and breast cancer rates have leveled off again.
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