Guide :

Risks associated with mastectomy in a patient with brain metastases

Hi, My sister has been diagnosed with breast cancer three years ago and was also diagnosed with brain metastases as a result of breast cancer. She has been under mastectomy surgery once and now she has to go for a mastectomy for her other breast. She has just finished a round of radiation therapy for her brain metastasis. I wonder if there are any risks associated with anesthesia that she will receive in the process of mastectomy surgery. Specifically, does anesthesia for her mastectomy jeopardize her brain function in the process? Would oncologists recommend this type of operation for a per

Research, Knowledge and Information :


New risk factors for brain metastases in breast cancer ...


Nearly one-fifth of all metastatic breast cancer patients develop brain metastases and have significantly shorter overall survival than patients who do not have brain ...
Read More At : www.sciencedaily.com...

Breast cancer brain metastases: the last frontier ...


Breast cancer is a common cause of brain metastases, with metastases occurring in at least 10–16 % of patients. Longer survival of patients with metastatic breast ...
Read More At : ehoonline.biomedcentral.com...

Risk factors for brain metastasis in breast cancer patients ...


Risk factors for brain metastasis in ... is associated with increased risk of lymph ... breast cancer patients with brain metastasis were more ...
Read More At : www.univadis.com...

What are the risk factors for brain metastasis in breast ...


What are the risk factors for brain metastasis in breast cancer patients? ... brain metastases was associated with ... risk of brain metastasis and ...
Read More At : www.nature.com...

Management of brain metastases in breast cancer - UpToDate


Breast cancer is the second most common cancer associated with brain metastases in the United States. As patients with advanced breast cancer live longer, the ...
Read More At : www.uptodate.com...

Risk factors and survival outcomes in patients with brain ...


Development of central nervous system (CNS) metastases in breast cancer (BC) is associated with poor prognosis. The incidence of CNS metastases in metastatic BC is ...
Read More At : link.springer.com...

BRCA1 Mutations Are Associated with Increased Risk of Brain ...


September 27, 2016—Boston, Massachusetts--Germline BRCA1 mutation in breast cancer patients appears to be associated with an increased risk of brain metastasis ...
Read More At : www.practiceupdate.com...

Researchers uncover new risk factors for brain metastases in ...


Nearly one-fifth of all metastatic breast cancer patients develop brain metastases and have significantly shorter overall survival than patients who do not have brain ...
Read More At : medicalxpress.com...

Predictive factors of brain metastasis in patients with ...


factors associated with metastasis to the brain of ... breast cancer patients for risk of brain metastasis, ... metastasis in patients with breast cancer, ...
Read More At : rd.springer.com...

Effect of age and biological subtype on the risk and timing ...


Feb 23, 2014 · Effect of age and biological subtype on the risk and timing of brain metastasis in breast cancer patients ... associated with differing risks of brain ...
Read More At : www.ncbi.nlm.nih.gov...

Suggested Questions And Answer :


Risks associated with mastectomy in a patient with brain metastases

These are all questions that would best be posed to her treatment team, who would have all of her medical hx, current health status, tests results,etc. needed to formulate the best treatment plan for her. Best weishes to both you and your sister...
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Being overweight and brain cancer

Being overweight isn't listed as a factor for brain tumors apparently. Weird.
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Benefit of Tamoxifen

personally, I don't trust cancer period. It's too unpredictable.  I would stay on your course of treatment anyway.  Im sure the doctor has you on it for a reason.  Trust his judgement.  It must be tough going thru menopause at the same time.  Invasive ductal carninoma is what it is.  Invasive means it travels and spreads.  There is nothing to say it won't spread to more lymph nodes.  I would surely stay on tamoxifen.  Hopefully you can put up with it four more years.  Then you will probably be able to stop taking it.   You might ask the doctor for something different.   Good luck with it,.   sammie
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confused....

  May I ask, r u sure it doesn't say beaking instead of breaking??
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Seizures after ACTH testing

I know you have to be off the meds to test. Most docs try to do it by getting the person on HC (if on pred) for a few weeks while the half life of pred goes off, The patient then simply skips the afternoon dose of HC, testing in the morning, and thus you are 24 hours off with minimal risk and you can dose right after the test. I have not heard of having issues due to the test - I know the test is hard for some people - chills, veins, etc. but I had not heard of or had any of my friends have anything that extreme like seizures or organ failure...
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post-operative care and diabetes

Diabetes aside I do not believe it is appropriate for your mother to have this procedure as an outpatient. I feel very strongly about this and would NOT stand for it for my mother or anyone else of your mothers age and with her medical problems. If there is any way possible that you can object, PLEASE DO SO .... this is not adequate medical care.
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New CM1 Patient - Pain-Risk Tipping Point for Surgery?

  Hi and welcome to the Chiari forum.   I have to start off with ur breathing issues r not minor...and bcuz u r used to ur symptoms and have adjusted to them also does not mean they r not significant. As for if u r a surgical candidate or not will be up to u and ur NS...and if u have effects from chiari affecting ur overall health. U mentioned u know u have Ehlers-Danlos, and chiari....well u also want to know if u have syringomyelia, and tethered cord. A CINE MRI to check for a CSF obstruction and overcrowding is one step.....then a MRI of the thoracic and lumbar spine to rule out tethered cord and disk issues. What u need to know is these issues u feel, no matter if u consider them minor r disrupting  the signals going thru ur nerves, this disruption left untreated can result in perm nerve damage...and with damaged nerves u may not feel the pain, so not feeling intense pain is not always a good sign when we r talking about a neuro condition.   U also will want a true chiari specialist- see our list of Drs to use as a research tool, the list is not meant as a referral-http://www.medhelp.org/posts/Chiari-Malformation/LIST-OF-CHIARI-SPECIALISTS/show/1503562 From what u have listed ur symptoms appear more than minor to me... Please do see a good chiari dr and get a few opinions to see which  is hte best course of action for u.    "selma"
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Individuals with social phobia have too much serotonin -- not too little

I answered this on his private site.  He's got the whole notion of serotonin and how antidepressants wrong.  If you go on his private site you'll see my answer as to why this post is not useful to anyone with anxiety at this time.
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MS patient with low grade Chiari

Hello and Welcome to the Chiari forum!! Wow..they had a lot to say on your MRI!! I took a medical terminology class but most of that is way out of my league. It does seem to me that they find that there is overcrowding of your cerebellum accompanied with a slight herniation into the foramen magnum ( the opening in your skull where the spinal cord passes through). I am thinking that the herniation must be less than 5 mm which is why the called it Chiari 0. From what I understand, they couldn't see any kinking of the brainstem (very good), no syrinx or widening of the spinal canal, and no hydrocephalus(build up of fluid in the brain). All of this is good but that doesn't mean that Chiari is not causing symptoms because your CSF flow could be blocked. It also mentions some kind of change in the atlanto-odontoid joint ..which says to me that there are some changes in your cervical spine that are consistent with Chiari. I was told by my NS that usually it is a change in the cervical spine that causes Chiari to become symptomatic. It sounds like all in all that they don't think Chiari is causing much of a problem and that they are finding more evidence that it's MS?? Just a guess there though.. May I ask why you had a MRI? Was it a regular MS followup or was it due to some new symptoms? It will be really hard to differentiate MS symptoms from Chiari ones b/c they are so much the same...most of us are first tested for MS when our symptoms appear. My suggestion is to try and get a Chiari specialist to look at your scans..they are the best ones to give you an idea of how much trouble the Chiari is causing. We have a list of specialists here that the forum members have put together. http://www.medhelp.org/posts/Chiari-Malformation/LIST-OF-CHIARI-SPECIALISTS/show/1121460 Or for a small fee you can send your scans into The Chiari Institute and they will look them over and let you know if they think it something they would look into. As for if it will get worse...if you NS determines that it is causing some symptoms for you, most of us do find over time that it does get worse. Some of us progress quickly and others it has been causing them symptoms for years. Again, this is another thing that really only a NS can tell you b/c they need to assess the overcrowding, whether there is CSF blockage and then compare that to your symptoms. Good luck to you...I am really truly sorry that you have both conditions to deal with. Take care and please let us know what you find. Carolyn
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Slow Coronary Flow Disease in Normal epicardial Coronary Arteries

Hi, As mentioned from the other post, this is an  increasingly recognized as a separate clinical entity along with the “classic” coronary syndrome X  in the framework of microvascular angina. The mechanism of this phenomenon remains unknown and further studies are continuously being done describe the clinical characteristics, including the prognosis, of these patients and to identify potential treatment (ref:http://www.ncbi.nlm.nih.gov/pubmed/18503124) It is best that you discuss this with your attending physician for proper evaluation. Factors such as your symptoms, diagnostic results and medical history are important considerations also. Take care and best regards.
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